要实现ADFS 2016 OpenID Connect并在一个ASP.NET Core Web应用程序中使用多个API资源，可以按照以下步骤进行设置和编码：

1. 在ASP.NET Core Web应用程序中安装以下NuGet包：

   • Microsoft.AspNetCore.Authentication.OpenIdConnect
   • Microsoft.IdentityModel.Protocols.OpenIdConnect
   • Microsoft.IdentityModel.Tokens
   • Microsoft.AspNetCore.Authentication.Cookies

2. 在ASP.NET Core Web应用程序的Startup.cs文件中配置OpenID Connect身份验证服务和API资源：

public void ConfigureServices(IServiceCollection services)
{
    // 配置OpenID Connect身份验证服务
    services.AddAuthentication(options =>
    {
        options.DefaultScheme = CookieAuthenticationDefaults.AuthenticationScheme;
        options.DefaultChallengeScheme = OpenIdConnectDefaults.AuthenticationScheme;
    })
    .AddCookie()
    .AddOpenIdConnect(options =>
    {
        options.Authority = "https://your-adfs-server/adfs";
        options.ClientId = "your-client-id";
        options.ClientSecret = "your-client-secret";
        options.ResponseType = "code";
        options.Scope.Add("openid");
        options.SaveTokens = true;
    });

    // 配置API资源
    services.AddAuthorization(options =>
    {
        options.AddPolicy("Api1Policy", policy =>
        {
            policy.AuthenticationSchemes.Add(JwtBearerDefaults.AuthenticationScheme);
            policy.RequireAuthenticatedUser();
            policy.RequireClaim("aud", "api1-resource");
        });

        options.AddPolicy("Api2Policy", policy =>
        {
            policy.AuthenticationSchemes.Add(JwtBearerDefaults.AuthenticationScheme);
            policy.RequireAuthenticatedUser();
            policy.RequireClaim("aud", "api2-resource");
        });
    });

    services.AddControllers();
}

public void Configure(IApplicationBuilder app, IWebHostEnvironment env)
{
    // ...

    // 启用身份验证中间件
    app.UseAuthentication();

    // 启用授权中间件
    app.UseAuthorization();

    // ...

    app.UseEndpoints(endpoints =>
    {
        endpoints.MapControllers()
            .RequireAuthorization("Api1Policy"); // 要求API1资源进行身份验证和授权
    });

    app.UseEndpoints(endpoints =>
    {
        endpoints.MapControllers()
            .RequireAuthorization("Api2Policy"); // 要求API2资源进行身份验证和授权
    });
}

3. 在API资源的控制器中使用授权属性来限制访问：

[Authorize("Api1Policy")]
[Route("api/[controller]")]
[ApiController]
public class Api1Controller : ControllerBase
{
    // ...
}

[Authorize("Api2Policy")]
[Route("api/[controller]")]
[ApiController]
public class Api2Controller : ControllerBase
{
    // ...
}

这样，你就可以在ASP.NET Core Web应用程序中使用ADFS 2016 OpenID Connect并限制不同API资源的访问。请根据你的具体情况修改配置和代码示例中的参数和值。